ORLANDO, FL (UroToday.com) - Dr. Robert Uzzo argued for observation in many renal masses. Despite the fact that kidney cancer is a deadly disease, it is additionally heterogeneous. Despite the fact that kidney cancer is a deadly disease, it is plus heterogeneous. He performed a meta-analysis to compare partial nephrectomy, cryoablation, radiofrequency ablation or surveillance. The input showed that the patients selected for surgery were typically younger. Follow-up in the literature is twice as expanded (33 months) compared to cryotherapy or RFA. Relative risk of local recurrence was 7-fold for cryotherapy and 18-fold for RFA. Despite that, very few of the tumors metastasized.

In his series one-third of small renal masses do not grow by 3 years. that is likely due to many being benign. Lesions tumor growth.

A nomogram developed by the Cleveland Clinic helps to stratify risk of progression to metastatic disease. He presented an argument for 5-year competing risk of death in older patients. A 72 year old man with a 2cm lesion has a 2% risk of death from kidney cancer compared to a 20% risk of dying from other causes. He compared observation to the complications of ablative therapy

or partial nephrectomy. Overall, Dr. Uzzo presented a compelling argument for observation in appropriate patients.

Presented by Robert Uzzo, MD, at the Annual Meeting of the American Urological organization (AUA) - May 17 - 22, 2008. Orange County Convention Center - Orlando, Florida, USA.

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Original post by Mallows